i-FACTOR Bone Graft is based on the biological activity of the synthetically derived 15-amino acid peptide found naturally in Type I human collagen. This 15-amino acid peptide (P-15) is responsible for the attachment and proliferation of osteogenic cells. These cells have an affinity for and attach to the P-15 found in i-FACTOR Bone Graft in a similar way they would naturally with Type I collagen in bone.
i-FACTOR Bone Graft facilitates and expedites the ingrowth of bone by promoting the migration of mesenchymal stem cells and other progenitor cells from surrounding tissue.
i-FACTOR
The FIRST Peptide Enhanced Bone Graft approved by the FDA for Spine Surgery
 Rely on Evidence |  i-FACTOR Syringe |  1cc 2.5cc 5cc |  Level-1 Human Evidence |  Cerapedics |
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Product Details
Documents
FDA PMA Study
Burden of Proof
Breakthrough Technology
i-FACTOR Brochure
The high affinity between cells and P-15 supports the physiological mechanism of action in which cells bind to the P-15 and “turn on” to perform their genetically programmed job of making bone.
The novel i-FACTOR Bone Graft “Attract, Attach, Activate” mechanism of action enhances the body’s natural bone healing process.
